The Purpose of SeguraBlawg's Vitamin D3 Blawg

I have come to believe that many of the diseases that plague us have, as their root cause, a gross insufficiency/deficiency of Vitamin D3, and its bioavailable metabolized product, calcitriol. In the pages that follow you will find scores of medical journal articles which document, via carefully constructed and executed scientific experimentation, the myriad disease-inducing effects of chronic Vitamin D3 deficiency in the human body.

More importantly, this body of scientific medical research also underscores our ever expanding awareness of the hundreds of salutary effects flowing from achieving and maintaining optimal Vitamin D3 serum levels.

Through this Vitamin D3 Blawg I seek to enlighten and encourage those who quietly, at times, desperately, suffer from Vitamin D3-mediated diseases they long believed to be irremediable, but which may now soon be understood and overcome through the conscientious application of rigorous scientific medical investigation, experimentation and discovery.

Vitamin D3's Essential Role in Maintaining Good Health and Preventing Deadly, Debilitating Diseases

Vitamin D3's Essential Role in Maintaining Good Health and Preventing Deadly, Debilitating Diseases
Schematic View of Sources of Vitamin D3 and Its Role in Maintaining Health and Preventing Multiple Deadly and Debilitating Diseases, Including Cancer, Hypertension, Cardiac Disease, Diabetes, Osteoporosis, Multiple Sclerosis, Psoriasis, Asthma, Allergies, Depression, SAD, ADD, ADHD, Among Many Others.

Saturday, December 13, 2008

25-Hydroxyvitamin D3, the prohormone of 1,25-dihyd...[Cancer Epidemiol Biomarkers Prev. 2000] - PubMed Result

25-Hydroxyvitamin D3, the prohormone of 1,25-dihyd...[Cancer Epidemiol Biomarkers Prev. 2000] - PubMed Result

"25-OH-D3 and 1,25(OH)2D3 each inhibited growth in a dose- and time-dependent manner. Growth inhibition was evident at 1 nM, and maximal inhibition was observed at 100 nM within 10-12 days of exposure. The potencies of 25-OH-D3 and 1,25(OH)2D3 were not significantly different. These data demonstrate that 25-OH-D3, which previously was thought to have little biological activity, can become a potent antiproliferative hormone for prostatic cells that express 1-alpha-hydroxylase. Because 25-OH-D3 exhibits similar potency to 1,25(OH)2D3 but is less calcemic, 25-OH-D3 may offer a safer option than 1,25(OH)2D3 for prostate cancer therapy. Moreover, because 25-OH-D3 is produced endogenously from vitamin D, these findings support a potential role for vitamin D in the chemoprevention of prostate cancer."
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